Investigació Aplicada en Malalties Respiratòries

Research team

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Gianluigi Li Bassi

Research Physician
glibassi(ELIMINAR)@clinic.ub.es

Doctorate in Medicine from the University of Milan. He is a specialist in anesthesia and critical care. He takes part in the animal model line and his research focuses on finding new strategies to reduce the incidence of intubation-associated pneumonia.

In the lines of noninvasive ventilation (NIV) and ventilator-associated pneumonia (VAP), he aims to answer the following questions:

  • Leak-proof cuff with continuous aspiration of subglottic secretion: Is it feasible to prevent aspiration and translocation of bacteria from the oropharynx into the lower airways?
  • Enhancing clearance of airway secretions in intubated and mechanically ventilated patients: Could either ventilatory settings or an external mechanical device prevent retention of mucus following tracheal intubation?
  • Silver-coated endotracheal tubes: Is it possible to prolong the bactericidal effect of silver coated tubes?

His line of research focusses on devising and evaluating new devices and strategies to prevent intubation-associated pneumonia and translate the findings to ICU patients. In particular, he is interested in finding preventive approaches to maintaining physiologic airway sterility, following tracheal intubation.

His line of research could greatly reduce the incidence of intubation-associated pneumonia, which is still the second most common acquired infection in critically ill intubated and mechanically ventilated patients. Moreover, enhancing clearance of mucus could prevent pulmonary complications, such as the adverse effects of deep-tracheal suction; reduce the length of intubation time and reduce ICU mortality and morbidity.