Investigació Aplicada en Malalties Respiratòries

Research team


Carles Agustí

Senior Researcher

Publications at PubMed

Doctor of Medicine from the University of Barcelona. Specialist in respiratory medicine and leader of the research line on the study of pulmonary infiltrates in immunocompromised patients. He also evaluates the role of immunomodulating drugs, such as corticosteroids, in the treatment of severe community-acquired pneumonia.

This line aims to answer questions such as what is the best moment to perform invasive tests when studying immunocompromised patients with pulmonary infiltrates, which endoscopy techniques are most useful in evaluating immunocompromised patients, do biomarkers exist that make it possible to suspect or rule out a specific type of pulmonary complication?

The results of his investigations may improve the course of immunocompromised patients with lung infections by reducing mortality, clinical complications and length of hospital stay, in order to provide better quality of life.


  • Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs

    Martinez-Olondris P, Rigol M, Soy D, Guerrero L, Agusti C, Quera MA, Li Bassi G, Esperatti M, Luque N, Liapikou M, Filella X, Marco F, de la Bellacasa JP, Torres A.

    Crit Care Med. 2011 Sep 15.

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  • Prevalence of dihydropteroate synthase genotypes before and after the introduction of combined antiretroviral therapy and their influence on the outcome of Pneumocystis pneumonia in HIV-1-infected patients

    Alvarez-Martínez MJ, Miró JM, Valls ME, Mas J, de la Bellacasa JP, Sued O, Solé M, Rivas PV, de Lazzari E, Benito N, García F, Agustí C, Wilson PE, Gatell JM, Jiménez de Anta MT, Meshnick SR, Moreno A.

    Diagn Microbiol Infect Dis. 2010 Sep;68(1):60-5.

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  • A randomized study of endobronchial valves for advanced emphysema

    Sciurba FC, Ernst A, Herth FJ, Strange C, Criner GJ, Marquette CH, Kovitz KL, Chiacchierini RP, Goldin J, McLennan G; VENT Study Research Group.

    N Engl J Med. 2010 Sep 23;363(13):1233-44.

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  • Linezolid limits burden of methicillin-resistant Staphylococcus aureus in biofilm of tracheal tubes.  

    Fernández-Barat L, Ferrer M, Sierra JM, Soy D, Guerrero L, Vila J, Li Bassi G, Cortadellas N, Martínez-Olondris P, Rigol M, Esperatti M, Luque N, Saucedo LM, Agustí C, Torres A.  

    Crit Care Med. 2012 Aug;40(8):2385-9.

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Improving the course of immunocompromised patients in lung infections and their quality of life are key elements of his research

Involved in the following lines