Pulmonary complications in immunocompromised (IC) patients
Objectives
- Study of infectious complications in immunocompromised patients
- Role of fiberoptic bronchoscopy in lung infections in IC patients
- Study of late noninfectious complications in patients with hematopoietic precursor-cell transplants (HPT)
Projects in Progress
- Utility of early bronchoscopy in the study of pulmonary complications in IS patients
- Role of the determination of galactomannan antigen in bronchoalveolar lavage fluid
Milestones Achieved
- Identification of factors for the prognosis of pulmonary complications in IC patients
- Utility of endoscopic techniques in pulmonary complications in IC patients
Future Challenges
- Identification of new biomarkers in infectious complications in IC patients
- Study of pathogenic mechanisms of post-HPT obliterating bronchiolitis
Publications
Prognostic factors of non-HIV immunocompromised patients with pulmonary infiltrates
Rañó A, Agustí C, Benito N, Rovira M, Angrill J, Pumarola T, Torres A
Chest 2002; 122: 253-261
Pulmonary infiltrates in non-HIV immunocompromised patients. A diagnostic approach using non-invasive and bronchoscopic techniques
Rañó A, Agustí C, Jimenez P, Angrill J, De Benito N, Danés C, González J, Rovira M, Pumarola T, Moreno A, Torres A
Thorax 2001; 56: 379-387
Inflammatory response associated with pulmonary complications in non-HIV immunocompromised patients
Agustí C, Rañó A, Rovira M, Filella X, Benito N, Moreno A, Torres A.
Thorax 2004; 59: 1081-1088
Significance of the presence of lymphocytes in the cytological analysis of transbronchial needle aspiration
Lucena CM, Agustí C, Martínez-Olondris P, Cano-Jiménez E, Marrades RM, Ramírez J, Sánchez M, Arguis P, Xaubet A.
Arch Bronconeumol. 2011 Mar;47(3):122-7.
Prevalence of dihydropteroate synthase genotypes before and after the introduction of combined antiretroviral therapy and their influence on the outcome of Pneumocystis pneumonia in HIV-1-infected patients
Alvarez-Martínez MJ, Miró JM, Valls ME, Mas J, de la Bellacasa JP, Sued O, Solé M, Rivas PV, de Lazzari E, Benito N, García F, Agustí C, Wilson PE, Gatell JM, Jiménez de Anta MT, Meshnick SR, Moreno A.
Diagn Microbiol Infect Dis. 2010 Sep;68(1):60-5.
A randomized study of endobronchial valves for advanced emphysema
Sciurba FC, Ernst A, Herth FJ, Strange C, Criner GJ, Marquette CH, Kovitz KL, Chiacchierini RP, Goldin J, McLennan G; VENT Study Research Group.
N Engl J Med. 2010 Sep 23;363(13):1233-44.
People working in this line
-
Carles Agustí
(Responsible)
Lines list
- Animal Model
- Bronchiectasis non associated to Cystic Fibrosis (BQ-noFQ), Cystic Fibrosis (CF) and immune deficiencies
- Community-Acquired Pneumonia (CAP)
- Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
- Networks, European Projects and Collaborations
- Noninvasive Ventilation (NIV)
- Pulmonary complications in immunocompromised (IC) patients
- Translational research laboratory for advanced microbiology diagnosis and pathogen-host response in respiratory infections
- Ventilator-Associated Pneumonia (VAP)
