Investigació Aplicada en Malalties Respiratòries

Research Lines

Pulmonary complications in immunocompromised (IC) patients

  • Study of infectious complications in immunocompromised patients
  • Role of fiberoptic bronchoscopy in lung infections in IC patients
  • Study of late noninfectious complications in patients with hematopoietic precursor-cell transplants (HPT)
Projects in Progress
  • Utility of early bronchoscopy in the study of pulmonary complications in IS patients
  • Role of the determination of galactomannan antigen in bronchoalveolar lavage fluid
Milestones Achieved
  • Identification of factors for the prognosis of pulmonary complications in IC patients
  • Utility of endoscopic techniques in pulmonary complications in IC patients
Future Challenges
  • Identification of new biomarkers in infectious complications in IC patients
  • Study of pathogenic mechanisms of post-HPT obliterating bronchiolitis


  • Prognostic factors of non-HIV immunocompromised patients with pulmonary infiltrates

    Rañó A, Agustí C, Benito N, Rovira M, Angrill J, Pumarola T, Torres A

    Chest 2002; 122: 253-261

    More information

  • Pulmonary infiltrates in non-HIV immunocompromised patients. A diagnostic approach using non-invasive and bronchoscopic techniques

    Rañó A, Agustí C, Jimenez P, Angrill J, De Benito N, Danés C, González J, Rovira M, Pumarola T, Moreno A, Torres A

    Thorax 2001; 56: 379-387

    More information

  • Inflammatory response associated with pulmonary complications in non-HIV immunocompromised patients

    Agustí C, Rañó A, Rovira M, Filella X, Benito N, Moreno A, Torres A.

    Thorax 2004; 59: 1081-1088

    More information

  • Significance of the presence of lymphocytes in the cytological analysis of transbronchial needle aspiration

    Lucena CM, Agustí C, Martínez-Olondris P, Cano-Jiménez E, Marrades RM, Ramírez J, Sánchez M, Arguis P, Xaubet A.

    Arch Bronconeumol. 2011 Mar;47(3):122-7.

    More information

  • Prevalence of dihydropteroate synthase genotypes before and after the introduction of combined antiretroviral therapy and their influence on the outcome of Pneumocystis pneumonia in HIV-1-infected patients

    Alvarez-Martínez MJ, Miró JM, Valls ME, Mas J, de la Bellacasa JP, Sued O, Solé M, Rivas PV, de Lazzari E, Benito N, García F, Agustí C, Wilson PE, Gatell JM, Jiménez de Anta MT, Meshnick SR, Moreno A.

    Diagn Microbiol Infect Dis. 2010 Sep;68(1):60-5.

    More information

  • A randomized study of endobronchial valves for advanced emphysema

    Sciurba FC, Ernst A, Herth FJ, Strange C, Criner GJ, Marquette CH, Kovitz KL, Chiacchierini RP, Goldin J, McLennan G; VENT Study Research Group.

    N Engl J Med. 2010 Sep 23;363(13):1233-44.

    More information