Investigació Aplicada en Malalties Respiratòries

Research Lines

Pulmonary complications in immunocompromised (IC) patients

Objectives
  • Study of infectious complications in immunocompromised patients
  • Role of fiberoptic bronchoscopy in lung infections in IC patients
  • Study of late noninfectious complications in patients with hematopoietic precursor-cell transplants (HPT)
Projects in Progress
  • Utility of early bronchoscopy in the study of pulmonary complications in IS patients
  • Role of the determination of galactomannan antigen in bronchoalveolar lavage fluid
Milestones Achieved
  • Identification of factors for the prognosis of pulmonary complications in IC patients
  • Utility of endoscopic techniques in pulmonary complications in IC patients
Future Challenges
  • Identification of new biomarkers in infectious complications in IC patients
  • Study of pathogenic mechanisms of post-HPT obliterating bronchiolitis

Publications

  • Prognostic factors of non-HIV immunocompromised patients with pulmonary infiltrates

    Rañó A, Agustí C, Benito N, Rovira M, Angrill J, Pumarola T, Torres A

    Chest 2002; 122: 253-261

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  • Pulmonary infiltrates in non-HIV immunocompromised patients. A diagnostic approach using non-invasive and bronchoscopic techniques

    Rañó A, Agustí C, Jimenez P, Angrill J, De Benito N, Danés C, González J, Rovira M, Pumarola T, Moreno A, Torres A

    Thorax 2001; 56: 379-387

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  • Inflammatory response associated with pulmonary complications in non-HIV immunocompromised patients

    Agustí C, Rañó A, Rovira M, Filella X, Benito N, Moreno A, Torres A.

    Thorax 2004; 59: 1081-1088

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