Investigació Aplicada en Malalties Respiratòries

Community-Acquired Pneumonia (CAP)

Objectives

• Study of microbial etiology and resistances of community-acquired pneumonia (CAP)
• Study of the inflammatory response and biomarkers of CAP for diagnosis and outcome
• Study of nonantibiotic therapy to reduce mortality of severe CAP

Projects in Progress

• Efficacy of intravenous corticosteroids in severe CAP Microbiology of CAP according to severity scores
• New inflammatory markers in CAP
• Epidemiology, inflammatory markers and outcomes of health care associated pneumonia (HCAP) in Spain
• Efficacy of (noncommercial) intravenous corticosteroids in severe CAP

Milestones Achieved

• Description of criteria for admission to ICU of patients with severe CAP
• Utility of biomarkers in CAP outcome
• Conceptualization of the lack of response to antibiotic therapy, implications for outcome and risk factors

Future Challenges

• Study of nonantibiotic therapies that modulate the inflammatory response and other routes in severe CAP
• Confirmation that HCAP are a different group of pneumonias from CAP
• Study of rapid diagnostic techniques for use in primary medicine in hospitalized patients