Investigació Aplicada en Malalties Respiratòries

Research team

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Antoni Torres

Coordinator and Team Leader
atorres(ELIMINAR)@ub.edu

Publications at PubMed

Professor in Medicine at the University of Barcelona (UB). He is considered a physician of reference both nationally and internationally in lung infections, including pneumonia, chronic obstructive pulmonary disease (COPD), bronchiectasis, immunocompromised patients, weaning, noninvasive ventilation (NIV), and acute respiratory distress syndrome (ARDS-ALI). He has published more than 200 original articles, he has an accumulated impact factor of more than 1390 and his published articles have received approximately 13,000 citations. He leads the research group on Management and prevention of infectious, interstitial and tumoral lung diseases of the August Pi i Sunyer Institute of Biomedical Research (IDIBAPS), from where he facilitates translational research studies.

He has taken part in more than 70 projects - 39 as principal researcher - and 27 studies of the Health Care Research Fund (FIS). His research receives support from many public bodies, including the following: Carlos III Health Institute (ISCII), CibeRes, IDIBAPS, and the European Union. He is currently involved in more than 30 national, European and other international projects. He coordinates a CIBER group on respiratory diseases (CibeRes) and takes part in the European projects, GRACE, MOSAR (WP3, WP4) and Theraedge.

This team mainly investigates community-acquired and intrahospital respiratory infections. The aim is to answer questions arising from clinical observation of patients that are not in the literature and to obtain results that can be quickly applied to patient care in the diagnosis, treatment and prevention of nosocomial pneumonia. The team also studies community-acquired respiratory infections, from where they approach important questions such as the decision to admit to hospital, the decision to admit to the intensive care unit (ICU), microbial etiology, diagnostic tests and the most appropriate treatment to use. Other central study topics include noninvasive ventilation for the treatment of severe acute respiratory failure and weaning from artificial ventilation. At the same time, an animal model of severe pneumonia has been developed that allows trans-species research.

The research group is characterized by the utility of its results and their impact on clinical practice. For example, it has described measures for preventing nosocomial pneumonia and criteria for admitting patients to the ICU in community-acquired pneumonia, which have been adopted universally. The group’s studies on noninvasive ventilation have meant that this technique can be applied to patients with severe respiratory failure and extrapolate it to routine clinical practice. It is research aimed at improving clinical practice and quality of patient care.



Publications

  • Validation of the American Thoracic Society–Infectious Diseases Society of America Guidelines for Hospital-Acquired Pneumonia in the Intensive Care Unit.

    Ferrer M, Liapikou A, Valencia M, Esperatti M, Theessen A, Martinez JA, Mensa J, Torres A.

    Clin Infect Dis 2010; 50: 945–952.

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  • Rethinking the concepts of community-acquired and health-care-associated pneumonia

    Ewig S, Welte T, Chastre J, Torres A

    LANCET INFECT DIS. 10:279-287

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  • Update in community-acquired and nosocomial pneumonia 2009

    Torres A, Rello J

    Am J Respir Crit Care Med. 2010 Apr 15;181(8):782-7.

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  • Changes in management of chronic obstructive pulmonary disease (COPD) in primary care: EMMEPOC study

    Soler N, Ballester E, Martin A, Gobartt E, Miravitlles M, Torres A

    Respir Med. 2010 Jan;104(1):67-75.

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  • Amoxicillin for acute lower-respiratory-tract infection in primary care when pneumonia is not suspected: a 12-country, randomised, placebo-controlled trial.  

    Little P, Stuart B, Moore M, Coenen S, Butler CC, Godycki-Cwirko M, Mierzecki A, Chlabicz S, Torres A, Almirall J, Davies M, Schaberg T, Mölstad S, Blasi F, De Sutter A, Kersnik J, Hupkova H, Touboul P, Hood K, Mullee M, O'Reilly G, Brugman C, Goossens H, Verheij T; on behalf of the GRACE consortium.

    Lancet Infect Dis. 2013 Feb;13(2):123-129.

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  • Noninvasive ventilation in acute hypercapnic respiratory failure caused by obesity hypoventilation syndrome and chronic obstructive pulmonary disease.    

    Carrillo A, Ferrer M, Gonzalez-Diaz G, Lopez-Martinez A, Llamas N, Alcazar M, Capilla L, Torres A.

    Am J Respir Crit Care Med. 2012 Dec 15;186(12):1279-85

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  • Association between systemic corticosteroids and outcomes of intensive care unit-acquired pneumonia.  

    Ranzani OT, Ferrer M, Esperatti M, Giunta V, Bassi GL, Carvalho CR, Torres A.  

    Crit Care Med. 2012 Sep;40(9):2552-61.

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  • An In Vitro Study to Assess Determinant Features Associated With Fluid Sealing in the Design of Endotracheal Tube Cuffs and Exerted Tracheal Pressures*    

    Li Bassi G, Ranzani OT, Marti JD, Giunta V, Luque N, Isetta V, Ferrer M, Farre R, Pimentel GL, Torres A.

    Crit Care Med. 2013 Feb;41(2):518-526.

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  • Effects of Manual Rib Cage Compressions on Expiratory Flow and Mucus Clearance During Mechanical Ventilation.    

    Martí JD, Bassi GL, Rigol M, Saucedo L, Ranzani OT, Esperatti M, Luque N, Ferrer M, Vilaro J, Kolobow T, Torres A.

    Crit Care Med. 2013 Jan 10.

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  • Linezolid limits burden of methicillin-resistant Staphylococcus aureus in biofilm of tracheal tubes.  

    Fernández-Barat L, Ferrer M, Sierra JM, Soy D, Guerrero L, Vila J, Li Bassi G, Cortadellas N, Martínez-Olondris P, Rigol M, Esperatti M, Luque N, Saucedo LM, Agustí C, Torres A.  

    Crit Care Med. 2012 Aug;40(8):2385-9.

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  • Direct analysis of bacterial viability in endotracheal tube biofilm from a pig model of methicillin-resistant Staphylococcus aureus pneumonia following antimicrobial therapy.  

    Fernández-Barat L, Li Bassi G, Ferrer M, Bosch A, Calvo M, Vila J, Gabarrús A, Martínez-Olondris P, Rigol M, Esperatti M, Luque N, Torres A.  

    FEMS Immunol Med Microbiol. 2012 Jul;65(2):309-17

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  • Effects of duty cycle and positive end-expiratory pressure on mucus clearance during mechanical ventilation*.  

    Li Bassi G, Saucedo L, Marti JD, Rigol M, Esperatti M, Luque N, Ferrer M, Gabarrus A, Fernandez L, Kolobow T, Torres A.  

    Crit Care Med. 2012 Mar;40(3):895-902.

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Torres

He is considered a physician of reference both nationally and internationally in lung infections and leads this IDIBAPS team from where he carries out translational research studies

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